… on their surface membrane, self DNA in serum was recognized and the animals developed
… inhibition might enhance the efficacy of cancer immunotherapy. In this context, preclinical …

… CpG ODN to act as adjuvants in animal models of immune deficiency triggered interest in
their potential to improve the response of geriatric animals … an adjuvant for sc immunotherapy …

… CpG DNA has been sought after as a therapeutic agent and … In the vertebrate immune
system, viral/microbial DNA that … adjuvants to be suitable for use in antitumor immunotherapy, …

… and synthetic DNA containing unmethylated CpG motifs. … ) are ideal agents for cancer
immunotherapy. As reported previously, … that synthetic CpGs are superb vaccine adjuvants in both …

… of CpG-ODNs as vaccine adjuvants and their antimicrobial function in domestic animals and
… activity is present only when the DNA contains unmethylated CpG deoxynucleotides (41, 42)…

… -guanosine (CpG) oligodeoxynucleotides (ODNs) as an adjuvant can … CpG
oligodeoxynucleotides (ODNs), a synthetic DNA oligonucleotide … Animals/cells used in …

… the use of CpG oligodeoxynucleotides (CpG-DNA), a B cell stimulant, in our adjuvant …
An effective adjuvant is necessary to develop animals with a vigorous, high affinity, antigen-…

… Citation30 CpG oligodeoxynucleotide (ODN) is a short single… other prokaryotes, but not in
vertebrate genomes. When this … idea, using CpG DNA not only as the immune adjuvant, but …

… the development of CpG-based immunotherapy will certainly … the potency of CpG DNA as
an adjuvant. Nishikawa's group … from four or six oligonucleotides, show promising efficacy in …

… the use of nucleic acids and oligonucleotides in cancer … played a critical role in their immune
adjuvant activity [81]. … memory that protected surviving animals from tumor rechallenge. The …